Course details of PH 419 - Physics of Biological Systems

Course Name Physics of Biological Systems
Total Credits 6
Type T
Lecture 2
Tutorial 1
Practical 0
Selfstudy 0
Half Semester N
Prerequisite 0.0
Text Reference R. Phillips, J. Kondev, J. Theriot & H. Garcia, Physical Biology of the Cell, Garland Science, 2012 K. Roberts, D. Bray, J. Lewis, M. Raff, A. Johnson, B. Alberts, Molecular Biology of the Cell, Garland Science, 1983 P. Nelson, Biological Physics, W.H. Freeman, 2013 J. Howard, Mechanics of Motor Proteins and the Cytoskeleton, Sinauer Associates, 2001 D. Bray, Cell Movements: From Molecules to Motility, Garland Science, 2001 D. Boal, Mechanics of the Cell, Cambridge University Press, 2012 H.C. Berg, Random Walks in Biology, Princeton University Press, 1983
Description Numbers and scales in Biology, temporal scales, kinetic processes, model systems. Diffusion in biological systems, Brownian motion, Reynold`s number, intraand intercellular transport. Pattern formation in biology, Turing model, Reactiondiffusion systems, mechanochemical coupling, patterns in development. Cell, cytoskeleton and motors, invitro and invivo measurements, models for filaments and motors, example systems, cell division and active matter. Chromatin structure and function, DNA and genes, nucleosomes and epigenetic regulation, higherorder structures. Gene expression, Role of noise, transcription and translation. Optional: Viral infections, lysis, lysogeny, horizontal gene transfer, immune responses. Proteinfolding and misfolding, aggregation and amyloids.
Last Update 25-10-2016 15:48:44.501663